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end bulk rna seq  (Broad Clinical Labs)


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    Structured Review

    Broad Clinical Labs end bulk rna seq
    A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. <t>Bulk</t> <t>RNA-seq</t> data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.
    End Bulk Rna Seq, supplied by Broad Clinical Labs, used in various techniques. Bioz Stars score: 96/100, based on 739 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/end+bulk+rna+seq/pmc12442335-49-20-28?v=Broad+Clinical+Labs
    Average 96 stars, based on 739 article reviews
    end bulk rna seq - by Bioz Stars, 2026-08
    96/100 stars

    Images

    1) Product Images from "Reduced ALDH2 in the respiratory tract associates with dysregulated alcohol metabolism and respiratory reactions in AERD"

    Article Title: Reduced ALDH2 in the respiratory tract associates with dysregulated alcohol metabolism and respiratory reactions in AERD

    Journal: The Journal of allergy and clinical immunology

    doi: 10.1016/j.jaci.2025.08.011

    A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. Bulk RNA-seq data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.
    Figure Legend Snippet: A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. Bulk RNA-seq data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.

    Techniques Used: Cell Culture, Derivative Assay, RNA Sequencing, In Vivo



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    A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. <t>Bulk</t> <t>RNA-seq</t> data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.
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    A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. <t>Bulk</t> <t>RNA-seq</t> data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.
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    A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. <t>Bulk</t> <t>RNA-seq</t> data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.
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    bulk rna-seq (after polya enrichment, paired-end strategy 2x150bp)  (Novogene)
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    A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. <t>Bulk</t> <t>RNA-seq</t> data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.
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    Image Search Results


    A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. Bulk RNA-seq data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.

    Journal: The Journal of allergy and clinical immunology

    Article Title: Reduced ALDH2 in the respiratory tract associates with dysregulated alcohol metabolism and respiratory reactions in AERD

    doi: 10.1016/j.jaci.2025.08.011

    Figure Lengend Snippet: A. ALDH2 transcript in cultured healthy nasal mucosa-derived ALIs with or without IL-4/13 (left) and in healthy lung-derived bronchial ALIs with or without IL-13 (right). B. ALDH2 protein levels in healthy nasal mucosa-derived submerged EpCs with or without IL-4/13. Data are shown as individual values. C. Bulk RNA-seq data of nasal scraping cells from paired patient samples (n=15) show the dupilumab-induced in vivo change in ALDH2 from baseline to after 1–3 months of dupilumab. Data are shown as individual values and means; analysis with paired t-tests.

    Article Snippet: Mature ALIs were stimulated with 10 ng/mL IL-4 and IL-13 for 7 days, then lysed with TCL buffer, and Smart-Seq2 paired-end bulk RNA-seq was performed by the Harvard-MIT Broad Institute.

    Techniques: Cell Culture, Derivative Assay, RNA Sequencing, In Vivo